A variety of erectile
dysfunction drugs are available on the market; however, side-effects and
effectiveness differ. A new study evaluated currently available erectile dysfunction
drugs in this regard. The study was published in the April edition of the
journal European
Urology by researchers at the University of Zurich, the Swiss Federal
Institute of Technology, and Maastricht University Medical Center in the
Netherlands.
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| Some drugs can cause unwanted sexual side effects in men |
Source: HEALTH
AND WELLNESS BLOG INDIA
The authors reviewed 82 studies of the drugs’ effectiveness
and 72 studies that assessed side-effects. They compared seven common erectile
dysfunction medications, which all belonged to a class of drugs known as
phosphodiesterase 5 inhibitors (PDE5i’s). They work by inhibiting an enzyme
that may reduce the potency of an erection. The investigators reviewed Viagra
(sildenafil), Cialis (tadalafil), Levitra (vardenafil), and Stendra (avanafil).
In addition, they evaluated Zydena (udenafil), Helleva (lodenafil), and Mvix
(mirodenafil), which are only available in other countries.
The aforementioned drugs are considered the first-choice
therapy for erectile dysfunction; however they are only effective for 60-80% of
men. The authors note that all the medications are more effective than s
placebo for treating erectile dysfunction, and are generally safe and well
tolerated. A 50 or 100 milligram (mg) dose of Viagra was found to be the
most effective treatment.
It was approximately 50% better than a placebo. Lower doses were less
effective. Stendra, in doses ranging from 50 to 200 mg, was one of the least
effective drugs studied; it was only 20-30% more effective than a placebo.
In regard to side-effects, the 50 milligram dose of Stendra
was reported to have the lowest rate of side effects among the drugs studied;
only 8.5% of the subjects reported side-effects. A 20 mg dose of Levitra had
the highest rate of side effects: 25%. Higher doses of Viagra and Cialis caused
side effects 21-22% of the time.
One side-effect of erectile dysfunction drugs is that they
are vasodilators (blood vessel dilators) that cause a drop in blood pressure.
Thus, they are not recommended for men taking nitrate-based heart medications
because they can cause a sharp drop in blood pressure. Other common side
effects include facial flushing, sinus congestion, headache, and upset stomach.
Cialis is the only medication that can be taken daily. It is also reported to
reduce the symptoms of benign prostate hypertrophy (BPH; enlarged prostate).
The other medications are only effective for a short period of time. Erectile
dysfunction drugs require a prescription; thus, which drug to take should be
thoroughly discussed with your physician.
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| Viagra, Cialis, Levitra, and Stendra |
Source: http://m.edtreatmentindia.com/
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