Most Floridians know that exposure to the sun increases
their risk of skin cancers, but until a published report in JAMA: Internal
Medicine last week, no one would have imagined that men taking Viagra (sildenafil) could
significantly raise their chances of developing melanomas which are potentially
the deadliest skin cancer.
Viagra may increase melanoma risk |
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Principal investigator Wen-Qing Li, PhD of Brigham and
Women’s Hospital in Boston knew that the drug had properties that could target
a specific mutation present in about half of melanomas and wondered whether
this effect could trigger metastasis (spread) of melanoma cells in the body.
In 2000, Li and colleagues questioned over 25,000 men in the
Health Professionals’ Followup Study about their use of Viagra for erectile dysfunction.
The average age of the participants was 64.8 years.
When the researchers analyzed the data from 2000 to 2010,
they found that after adjusting for known risk factors such as family history
or episodes of sunburns, those men who used Viagra were 84% more likely to
develop melanomas.
There was no apparent increased risk of developing other
skin cancers like basal cell or squamous cell for those men taking Viagra.
There was also no correlation between erectile dysfunction
itself and melanoma.
In his comments, Li wrote that “our study cannot prove cause
and effect.” He has proposed a longer follow-up study that would include
analysis of the dose of Viagra that individuals took and how often.
Of course, now that this study has been published and until
there is further research, physicians and patients have the dilemma of how to
interpret this information. Probably the best advice is to speak to your doctor
before taking Viagra and if you do take it, make sure you have regular skin
checks by either your primary physician or a dermatologist.
Viagra may increase the risk of a deadly form of skin cancer |
Source: http://www.edtreatmentindia.com/
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